Chronic disease risk reduction - PBL
Question:

Created by: Fan Gao, Chang Liu , Coral Cohen

PBL Design: Chronic disease risk reduction 

  1. Introduction to your assignment

  2. PBL requirements

  3. Guideline for students 

  4. Assessment system

  5. A great example

  6. Scientific background

  7. Reference

 

1. Introduction to your assignment

Chronic illnesses are a major risk for people's lives and they are very common, especially to elder people. According to a US Economist report, chronic illness accounts for more than 86% of deaths in EU countries. In Israel, approximately 21% of the population suffers from a chronic illness and approximately 65% of deaths in Israel are caused as a result of a chronic illness.

In addition, it can be observed that 40% of the population over the age of 15 suffer from chronic diseases and the percentage increases with age. The Economist's report suggests that communities and health systems need to allocate more resources to chronic disease treatment programs in order to reject or prevent the stages of human life that are at risk.

For example, according to Canary Foundation, cancer strikes at the US, one in three woman and one in two men in the US. More than 560,000 people die from it each year. The best chance to reduce these numbers it through early detection and intervention.

You need to plan PBL to help people identify chronic diseases in early stage and help with an appropriate treatment. The project must be achievable, innovative, simple to operate and based on scientific and engineering knowledge.

2. PBL Requirements

 

  • Analyze the existing problem and solutions with adequate academic references and critical thinking via different aspects like professional, physiological, marketing, etc. 

  • Working in small groups to come up with innovative solutions that are practical and expected by the market.

  • In small groups, every student is supposed to contribute to the project through their own way. The team should be well structured and sub-assignment should be distributed reasonably. 

  • The solution must incorporate scientific or engineering principles from different STEM subjects to develop interdisciplinary abilities.

  • The final outcome of the solution should be a functional product, model or prototype, with a document about marketing analysis and cost management, etc. All the demonstration needs to be uploaded to Augmented-world.

  • Offer high-level peer assessment and self-assessment about the work from self, group members and members from other groups, via innovation, workload, feasibility, etc.

 

3. Guideline 

 

3.1. Guidelines for Teachers

 

  • Divide students into small groups (3-5) from different majors.

  • Provide an introduction to the real-world problem and related references.

  • Give several examples of existing solutions and products.

  • Introduce basic STEM principles and study method which might be used in the program.

 

3.2. Guidelines for Students

 

  • Group icebreaking, leadership decision and group working structure;

  • Submit a report that analysis existing problem and solutions with adequate academic references and critical thinking via different aspects like professional, physiological, marketing, etc. [Assignment 1]

  • The group come up with an innovative solution for the existing problem and generate a report to clearly illustrate the whole idea and program schedule plan.[Assignment 2]

  • Teacher and TAs give feedback about [Assignment 1 and 2] and give instructions about the design and building part of the product.

  • Working on the program based on the schedule plan, at the midterm, students need to give a presentation about the progress they have made, a semi-finished model or a product is required.[Assignment 3]

  • At midterm presentation, students need to assess themselves works, their classmates’ works. Also, the teacher should assess every student’s work from the team and individual perspective.

  • Optimize the solution according to the assessments and continue finishing the program according to schedule, marketing issues should be involved. Write a report about the whole product with video or image illustration, upload all the material to Augmented-World.[Assignment 4]

  • Final bidding. All groups should present their final product to all the investors (other students and teachers). And receive assessments from all the investors.[Assignment 5]


 

4. Assessment System

 

4.1. Assessment Principles (how to evaluate PBL work)

 

4.1.1 Topic

The topic must balance both “problem solving” and “market situation”, which reflects professionalism. The topic focuses on the important problems, phenomena and development trends in the practice of real life. It reflects the team's ability to comprehensively apply the theoretical knowledge, methods, and techniques of innovation ability to solve practical problems.

 

4.1.2 Research content

On the basis of grasping the research status and development trend at home and abroad, this project conducts theoretical analysis and research on research issues and draws its own product(prototype) findings and conclusions through reasonable framework and structure.

 

4.1.3 Innovate methods

The innovate methods should match the life questions, be reasonable, standard and scientific, and encourage the attempt and absorption of new methods and technologies.

 

4.1.4 Product results 

The product results have certain innovation and research findings, research results for the practice of news dissemination have the application or reference value. The document should be upload on the augmented-world website.

 

4.2 Assessment Criteria

 

  • Assignment 1 [10% by the teacher]

  • Assignment 2 [10% by the teacher]

  • Assignment 3 [20%, 5% from self, 5% from peers, 10% from teacher]

  • Assignment 4 [20% by the teacher]

  • Assignment 5 [30%, by all investors]

  • Give high-quality assessments to self and others[10% by the teacher]

 

   The evaluation conclusion is divided into four kinds: excellent, good, pass and fail. Excellent: >=90; Good: 89-75; Pass: 74-60; Fail :<60.

 

5. A Great Example: Sticky Guard 

In light of the horrendous deaths caused by chronic illnesses and with inspiration from the recommendations for early detection that we showed at the first paragraph, in order to receive proper treatment before it is too late, especially for the old, we have devised an innovative invention that will make it easier for the public to monitor their health condition, alert them to potential risks and how to treat them before they develop into severe diseases.

Our invention consists of  small, flat and sticky sensors that can be pasted under a wristwatch or bracelet, and even above the skin, concealed with a make-up. The sensor is linked with a Bluetooth system to transfer heart pulse date to a dedicated application. In the application, the data information would be processed in an artificial intelligence system via deep learning technology, which could compare users' data with well-trained disease models including diabetes, high cholesterol, high blood pressure and sleep apnea. The application would alert you the chances of having a chronic illness, what percentage the risks is and what the suggested actions are.
 

Why choosing our product is the best for you?

 Today, many of the chronic illnesses can be discovered through extensive hospital examinations, but hospital admissions are not sufficient to get such a large number of patients in a short time. In addition, a large number of tests require the public to lose several working days and wait long queues, which means that they do not schedule medical tests in the first place and the cause in known  -  they detect serious illnesses only when the situation is too late and they are in real life danger. Therefore, our invention does not require the public to go through many tests but to examine their health condition effortlessly - all it takes is a dedicated sticker and a mobile phone of the subject or our family members who receive the information related to the risks relevant to the person being exposed.
Furthermore, a market survey showed that our invention is unique - no similar inventions exist.

We think our invention is very innovative because it can save lives without making a person obsessed with the hospital testing, without carrying an invasive or inconvenient device. Our sticker can be pasted on bracelets, watches and flying on bare skin without feeling it – a revolutionary solution. Older people who have difficulty understanding apps can also cope with its simple operation and even have the ability to automatically transfer information to family members' smartphones and for that reason – the family can follow the health condition of their beloved ones any time.

6. Scientific Background

Our main goal is to detect chronic diseases in advance through wearable devices. To realize our goal, we need some background knowledge in biology, electrical engineering and computer science. We will briefly describe the process about how to implement this idea. The first step is to use a photosensitive sensor to detect your heart rate. After we achieve the data, we will transfer it to the phone via bluetooth module. The application designed by us will be running on the mobile phone. The app keeps receiving new data from bluetooth and input it into the neural network, and return with results about the potential risk level to tell whether the user has a specific chronic disease or not.

 

6.1 Sensor Part

The device will contain four main modules: a green LED light, a photosensitive sensor, a bluetooth module and a power supply. We will use PPG  (Photo Plethysmo Graphy) method  to monitor the heartbeat. The LED light and the photosensitive sensor will be used to monitor periodic changes in the light intensity of blood flowing through the wrist. Green LED lights are used because the absorption of green light is the greatest in the presence of the red blood. This will make our detection result more accurate. The volume of blood in the skin pulsates with beats of the heart. When the heart contracts, the green light is absorbed maximumly and the light intensity is the least. When the heart diastole, green light is absorbed minimumly and light intensity is the greatest. This allows continuous monitoring to detect periodic changes in the intensity of light, which can then be converted into electrical signals to calculate the user's heart rate. After getting the data, we will transfer the pulse data to the app on the phone through the bluetooth module, which brings us to the second part.


6.2 Application Part

Designing applications on mobile phones mainly involves two parts: app development and algorithm design. As for the application development, we hope this app can be cross-platform in order to have more potential users. So we will use the Flutter framework developed by Google and write our program using Dart and Java. This will make our application executable on both iOS and Android platform. 

Algorithm design is the core of our device. Our goal is to calculate whether a user is at risk of developing a chronic disease through continuous heart rate input. In the past few years, neural networks have proved to be a powerful tool. On the mathematical level, with enough neurons and hidden layers, neural networks can fit into any function with high accuracy. So we're going to build a RNN (Recurrent Neural Network). This kind of neural networks are good at processing sequential data.

The only input of the neural network is the time series about the heartbeat. The output is the multi-classification result processed by softmax function. It will give the probability of various chronic diseases. Considering that we need to analyze a time series with great length, this will usually lead to the problem of gradient explosion/vanishing of the neural network. To avoid this situation, we will adopt special gate structures such as LSTM and GRU to prevent the forgetting of the past data. We will use GRU to save limited computing resources on mobile phones. Compared to the LSTM technique, GRU has lower performance requirements and can maintain nearly the same accuracy in the meantime.

After designing the structure of neural network, we need dataset to train the neural network. We need about 10 devices to collect data or to use public datasets directly. After training the neural network, we save the parameters of the network structure on the phone. The time series data of the user's heartbeat will be input into the process of forward computation of the neural network to get the probability of whether the user has any chronic diseases. When the probability exceeds the thresholds we set, the app will display users with different risk level tags and corresponding suggestions.

 

Our advertising!

 

7. Reference

 


https://www.youtube.com/watch?v=da8iw9hvQX4

https://www.emedicinehealth.com/ask_can_you_die_from_atrial_fibrillation/article_em.htm#ask_a_doctor

 

https://cardiogram.com/research/

 

https://www.ynet.co.il/articles/0,7340,L-4568363,00.html

 

http://www.canaryfoundation.org/wp-content/uploads/EarlyDetectionFactSheet.pdf

Provide an answer by clicking on "Map" and then on "Add an Answer".



Results, Analysis and Discussion


Comments:
1.  ZHANG TIAN (14.08.2019 pm 02.58.10)
Some suggestions
Your project is very interesting, its target group, its universality, which means that there will be a huge market. The corresponding solution is also very simple and straightforward. Heartbeat data does reflect many of the human body's problems and can be used as a feature of chronic diseases.
 Maybe you can add more sensors to provide more data sources. For example, blood flow rate sensors, pressure sensors. Smart medical care is a big market and a very challenging market. As far as the information I have learned, smart toilets are also a good choice. Excreted waste from the human body can also be used as a marker for disease diagnosis.
In addition, the privacy issue is also a range to consider. If this project is your entrepreneurial project, you should be cautious in terms of privacy policy.
2.  zhou lin (14.08.2019 pm 02.58.48)
some comments on the assignment and solution

 As for the Assignment :
I think the task is specific and meaningful but it may be difficult for students who don’t have any background knowledge in bio-technology. There do not provide core concept or indicator that can lead the students to think about or search.  I think it maybe better if they can provide the paper about biological detection. 

As for the solution :
I think it’s not innovative enough, as the Apple Watch has the similar function and more complete. The other thing is that the device is not completed enough.  Only detecting the heart rate can not sensor other chronic diseases like Chronic kidney disease, diabetes.So i think future market research is necessary , and they need to complain why the device is more innovative when compared to Apple Watch, like cost control?And the alternative technology  Urinalysis, can include more detections like kidney disease, liver disease, diabetes, it need to be considered. 

3.  zhou lin (14.08.2019 pm 03.10.23)
some comments by Guo Shi

The PBL about chronic disease risk reduction is meaningful with broad application prospects. Chronic disease is by far the leading cause of death in the world, accounting for 63% of all deaths. Monitoring chronic diseases and providing preventive measures for humans is extremely practical. There are several main contributions in this PBL work: First of all, the background offered the real-life meaning about the chronic disease with detailed data and video. Besides, in order to design this PBL, they give specific requirements, guide line, assessment system. Last but not the least, this PBL also offer a great example to refer. In general, this PBL work is excellent. And I have the following suggestions that can be referred to highlight this PBL work.

 

Firstly, chronic diseases such as heart disease, stroke, cancer, chronic respiratory diseases and diabetes are the leading causes of death in the world. There are many types of chronic diseases and the pathology is complicated. Therefore, I suggest that this PBL can focus on specific chronic disease and narrow the topic scope.

 

Secondly, the example in the PBL mentioned to use Recurrent Neural Network to structure the algorithm. However, Neural Network requires massive data. Considering the patient privacy, the data about the patients’ health, it is quite difficult to obtain such massive data, which makes the intelligent wristband impossible to detect accurately the chronic diseases. In my opinion, the detecting technology should be future considered to formulate your product.

 

Thirdly, the marketing about wearable device is hot and mature. The innovation and competition about your product should be further considered.

 

Overall, the PBL work about chronic disease risk reduction is well-motivated. Thank your team to show us such a meaningful project.

4.  Zijun Chan (14.08.2019 pm 03.12.08)
Feedback and Suggestion

Good job on your PBL. I feel that you did a great by being detailed and organized.

However, it seems impossible to reach the objective with the idea you have suggested, as it is not innovative and extensive enough. Since you are targeting chronic disease, heart rate alone will not be sufficient in concluding the possibility of a chronic disease. An individual who enters a Halloween scare house can get scared multiple times. The sudden and multiple changes in the heart rate detected by the wearable tracker from your idea can conclude as a heart attack, stroke, or chronic heart disease. Other chronic diseases that are not involving the heart will also not be detected since their symptoms will not be detected. 

But good job on the idea and innovation you have came up with!

5.  Gao Fan (14.08.2019 pm 11.28.06)
Our Video for Sticky Guard



History of edits
Edited BY: coral cohen Edit Date: 2019-08-18 09:51:51
Edited BY: coral cohen Edit Date: 2019-08-16 08:53:11
Edited BY: coral cohen Edit Date: 2019-08-16 08:52:54
Edited BY: coral cohen Edit Date: 2019-08-15 00:26:13
Edited BY: coral cohen Edit Date: 2019-08-14 13:37:55
Edited BY: coral cohen Edit Date: 2019-08-14 13:33:55
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